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Program

Thursday, November 26, 2015

8:30 –

Registration, coffee and tea

9:00 – 9:15

Monika M. Golas, Department of Biomedicine, Aarhus University, Aarhus, Denmark:

Opening and introduction

9:15 – 10:00

Noel Buckley, Department of Psychiatry, University of Oxford, Oxford, U.K.:

iPSCs as models of neuronal development and degeneration

10:00-10:45

Jens Magnusson, Karolinska Institute, Stockholm, Sweden:

Injury-induced neurogenesis in the adult striatum

10:45 – 11:30

Martin Røssel Larsen, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark:

Neuro-proteomics – investigation of signal transduction pathways in the brain

11:30 – 12:15

Andrea Faedo, Department of Biosciences, University of Milan, Milan, Italy:

A differentiation toolkit for the derivation of striatal neurons from pluripotent stem cells

12:15 – 13:30

Lunch

13:30 – 15:00

Poster session

15:00 – 15:45

Yvon Trottier, Institute of Genetics and Molecular and Cellular Biology, Illkirch, France:

Multifaceted dysfunctions caused by polyglutamine expansion in neurodegenerative disorders

15:45 – 16:30

Zoya Ignatova, Biochemistry and Molecular Biology, University of Hamburg, Hamburg, Germany:

Adventitious frameshifting at expanded CAG repeat sequences

16:30 – 17:00

Poul Henning Jensen, Department of Biomedicine, Aarhus University, Aarhus, Denmark:

Toxic mechanisms in synucleinopathies – a group of putative prion-like disorders

17:00 – 17:45

Eric Reits, Department of Cell Biology and Histology, University of Amsterdam, Amsterdam, The Netherlands:

Visualising the ubiquitin-proteasome system at work in Huntington's Disease

19:00 –

Dinner

Friday, November 27, 2015

8:30 –

Coffee and tea

9:00 – 9:45

Åsa Petersen, Translational Neuroendocrine Research Unit, Lund University, Lund, Sweden:

Hypothalamic pathology in Huntington disease

9:45 – 10:30

Stephan von Hörsten, Experimental Therapy, University Medicine, Erlangen, Germany:

Neurodevelopmental phenotype and intervention by HDACi in models of Huntington's disease

10:30 – 11:15

Sybille Krauß, German Center for Neurodegenerative Diseases, Bonn, Germany:

The MID1 protein complex: a regulator of expanded CAG repeat mRNAs

11:15 – 12:00

Willeke van Roon-Mom, Leiden University Medical Center, Leiden, The Netherlands:

Targeting the huntingtin mRNA to treat Huntington disease

12:00 – 13:30

Lunch

13:30 – 14:15

Anne Nørremølle, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark:

Mitochondrial dysfunction in Huntington’s disease: what went wrong?

14:15 – 14:45

Juan Yuan, Department of Biomedicine, Aarhus University, Aarhus, Denmark:

Differentiation of striatal medium spiny neurons from neural progenitor cells

14:45 – 15:15

Mark Denham, Dandrite, Aarhus University, Aarhus, Denmark:

Modelling Parkinson's Disease in vitro with human pluripotent stem cells

15:15 – 15:45

Marina Romero-Ramos, Department of Biomedicine, Aarhus University, Aarhus, Denmark:

Early change induced by alpha-synuclein over expression in the dopaminergic nitro-striatal system

15:45 – 16:15

Jens Randel Nyengaard, Stereology and EM Laboratory, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark:

Changes in dendrites, synapses and synaptic vesicles in stress

16:15 – 16:30

Monika M. Golas, Department of Biomedicine, Aarhus University, Aarhus, Denmark:

Concluding remarks