Final programme

Final Scientific Programme

The idea we have with the program is to cover topics which are of common interest for physiologists and pharmacologists and hopefully most if not all sessions will include talks which are focused on physiology and other talks focused on pharmacology.

Main Topics

  • Genito-urinay tract function
  • Inflammation
  • Membranes
  • Blood
  • Reproductive physiology
  • Regenrative medicine
  • Acid-base
  • Comparative physiology
  • Cardiovascular and lymphatics
  • Exercise
  • Immune system
  • Neuroscience
  • Endocrinology
  • Pain

Thursday, 17th September

18.00-21.00

Antikmuseet

Registration & Get-together at the Museum of Ancient Art (Antikmuseet) at Aarhus University
Update your insight into ancient Mediterranean culture by the small quiz we have prepared for you.

Friday, 18th September

8.00-

The Main Hall (Aulaen)

Registration

8.30-8.45

The Main Hall (Aulaen)

Welcome and opening remarks

8.45-9.45

The Main Hall (Aulaen)

Plenary and Public lectures

introduced by Jens Leipziger og Ole Bækgaard Nielsen, Aarhus University

8.45

 

Multimodular Optogenetics, Peter Hegemann, Biological Institute, Experimental Biophysics, Humboldt University, Berlin, Germany

9.15

 

Importance of mitochondrial adaptations to exercise training and performance, Carsten Lundby, Institute of Physiology, University of Zürich, Switzerland

9.45-11.15

Stakladen

 

Coffee, posters and exhibitors

11.15-12.45

Richard Mortensen stuen

 

Session 1 - To pee or not to be

Chairmen: Helle Prætorius and Robert Fenton, Aarhus University

11.15

1:1

Novel principles of renal K+ excretion, Larry Palmer, Dept. Physiology and Biophysics, Weill-Cornell Medical College, New York, USA

11.45

1:2

Regulation of NCC activity in renal K+ homeostatic response, Ewout Hoorn, Dept. Internal Medicine, Erasmus Medical Center Rotterdam, The Netherlands

12.05

1:3

The nature and regulation of flow-stimulated renal K+ excretion, Casper K Larsen, Dept. Biomedicine, Aarhus University, Denmark

12.25

1:4

Free communication 1: Is preeclampsia a variant of Liddles syndrome with enhanced activity of the epithelial sodium channel in the kidneys? Lise Hald Nielsen, Depart. Obstetrics and Gynecology, Aarhus University Hospital, Denmark

12.35

1:5

Free communication 2: A novel mutation affecting the arginine-137 residue of AVPR2 in male dizygous twins leads to congenital nephrogenic diabetes insipidus and attenuated urine exosome aquaporin-2, Gitte Ryge Hinrichs, Depart. Cardiovascular and Renal Research, University of Southern Denmark, Odense, Denmark

 

11.15-12.45

Preben Hornung

stuen

Session 2 - The hot soup

Chairmen: Eeva Moilanen, Tampere University, Thomas Kongsted Pedersen /Ulf Simonsen

11.15

2:1

Novel signal pathways in inflammation, Eeva Moilanen, The Immunopharmacology Research Group, Tampere University, Finland

11.45

2:2

The role of TRPA1 in pain and inflammation, Edward Högestatt, Dept. Laboratory Medicine, Lund University, Sweden

12.05

2:3

Inflammation as a therapeutic target in stroke, Stuart Allan, Faculty of Life Sciences, University of Manchester, UK

12.25

2:4

Free communication 1: Impaired Cyclooxygenase-2 Expression leads to aggravated renal fibrosis in response to unilateral ureteral obstruction in Mice, Signe Tofteng, Dept. Cardiovascular and Renal Research, University of Southern Denmark, Odense, Denmark

12.35

2:5

Free communication 2: Deficiency of Microsomal Prostaglandin E Synthase-1 Exacerbates Renal Fibrosis and inflammation in mice with unilateral ureteral obstruction, Chunling Li, Inst. of Hypertension, Sun Yat-sen University, Guangzhou, China

 

12.45-14.15

Stakladen

 

Lunch

14.15-17.00

The Main Hall (Aulaen)

Workshop - Year of the light

Chairmen: Elise Hedegaard, Aarhus University, Cristina Rius Leiva, CNIN Madrid

14.15

 

Welcome and Introduction by Andreu Llobera, Centre Nacional de Microelectronica, Spain

14.20

W1

Mechanogenetic Control of Endothelial Function, Dr. Guillermo Garcia-Cardena, Dept. Pathology, Harvard Medical School, USA

14.50

W2

Detection of cardiovascular diseases with a photonic approach: the Liphos project, Dr. Andreu Llobera, Centre Nacional de Microelectronica, Spain

15.10

W3

Living Photonics (LiPhos) Single Cell Analysis - Label Free Detection Methods, Damien King, Dublin City University, Ireland

15.30

W4

Microengineering Advanced In Vitro Technologies for Cell and Tissue Studies, Sabeth Verpoorte, University of Groningen, The Netherlands

15:50

 

Demonstration of LiPhos components

14.15-15.45

Richard Mortensen

stuen

Session 3 - Painful news

Chairmen: Jens Schouenborg, Lund University, Axel Forman, Aarhus University

14.15

3:1

A translational animal model of perceived pain magnitude using novel cortically implanted neural interfaces, Jens Schouenborg, Dept. Experimental Medical Science, Lund University, Sweden

14.45

3:2

Visceral pain: basic, translational and clinical perspectives, Asbjørn M Drewes, Dept. Clinical Medicine, Aalborg University Hospital, Denmark

15.05

3:3

Intrinsic cold and heat sensitivity of the nocisensor TRPA1, Peter Zygmunt, Dept. Clinical Chemistry and Pharmacology, Lund University, Sweden

15.25

3:4

Free communication 1: Aerobic exercise reduces pallesthesia and myofascial pain in man, Dejan Ristic, Dept. Health Science & Technology, Aalborg University, Denmark

15.35

3:5

Free communication 2: Changes of nervous conduction in transgenic mice with a changed metabolism of nerve fibres, Eike Schomburg, Max-Planck-Institute of Experimental Medicine, Göttingen, Germany

 

14.15-15.45

Preben Hornung

stuen

 

Session 4 - Lymphatic vessels - the ugly duckling of the vascular system

Chairmen: Helge Wiig, University of Bergen, Donna B Bødtkjer, Aarhus University

14.15

4:1

Lymphatic pump and valve dysfunction in genetic models of lymphatic disease Michael J Davis, Dept. Medical Pharmacology & Physiology, University of Missouri, USA

14.45

4:2

A new role of the interstitium and lymphatics in the development of hypertension Helge Wiig, Dept. Biomedicine, University of Bergen, Norway

15.05

4:3

Ion channels and lymphatic vessel function Donna B Bødtkjer, Dept. Biomedicine, Aarhus University, Denmark

15.25

4:4

Free communication 1: A functional role for pacemaking HCN channels in lymphatics? Jens Majgaard, Dept. Biomedicine, Aarhus University

15.35

4:5

Free communication 2: Voltage-gated sodium channels contribute to action potentials and spontaneous contractility in isolated human lymphatic vessels, Niklas Telinius, Dept. Biomedicine, Aarhus University

 

15.45

Stakladen

 

Posters, exhibitions – wine and snacks

17.30

 

Find your way to City Hall (20 min walking distance)

18.00

 

 

Welcome reception in City Hall

Saturday, 19th September

8.30-9.30

The Main Hall (Aulaen)

Plenary and Public lectures

introduced by Karl Erik Andersson, Aarhus University 

8.30

 

Physiology of ejaculation, Francois A Giuliano, Dept. Physical Medicine and Rehabilitation, Paris West Medical University, Orsay, France

9.00

 

The senescent endothelium, Paul M Vanhoutte, Dept. Pharmacology & Pharmacy, The University of Hong Kong, China

9.30-10.30

Stakladen

 

Coffee, posters and exhibitors

10.30-12.00

Richard Mortensen stuen

 

Session 5 - Building body parts

Chairmen: Karl-Dietrich Sievert, SALK University Hospital, Salzburg, Austria, Daniela Grimm, Aarhus University

10.30

5:1

New for Old - Addressing Bladder and Bowel Function with Tissue Engineering and Regenerative Medicine, Karl-Dietrich Sievert, SALK University Hospital Salzburg, Austria

11.00

5:2

Scaffold-free tissue engineering under microgravity conditions, Daniela Grimm, Dept. Biomedicine, Aarhus University, Denmark

11.25

5:3

Regenerating Organs and Tissues: from Bench to Bedside, May Griffith, Dept. Clinical and Experimental Medicine, Linköping University, Sweden

11.50

5:4

Free communication 1: High salt diet results in a hypertonic skin microenvironment, Elham Nikpey, Dept. Biomedicine, University of Bergen, Norway

10.30-12.00

Mogens Zieler stuen

 

Session 6 - Acid neighbors 

(co-sponsored with Physiological Society)
Chairmen: Jeppe Prætorius and Christian Aalkjær, Aarhus University

10.30

6:1

Carbonic anhydrase 7: Neuronal pH regulatory protein with morphogenic functions, Eva Ruusuvuori, Neuroscience Center, Helsinki University, Finland

11.00

6:2

Pathways for trafficking acid in multi-cellular cancer cell growths, Pawel Swietach, Dept. Physiology, Dept. Anatomy and Genetics, Oxford University, UK

11.20

6:3

Sensing and transport of HCO3- in the vascular wall, Ebbe Bødtkjer, Dept. Biomedicine, Aarhus University, Denmark

11.40

6:4

Free communication 1: Role of potassium channels in the regulation of proton (H+/K+ ATPase) pump activity in pancreatic duct epithelial cells, Christiane E. Sørensen, Dept. Biology, University of Copenhagen, Denmark

11.50

6:5

Free communication 2: Extracellular acidosis inhibits lymphatic vessel contractility, Anders Lerche Møller, Dept. Biomedicine, Aarhus University, Denmark

10.30-12.00

Preben Hornung

stuen

 

Session 7 - Novel aspects of genomics in physiology and pharmacology
Chairmen: Lise Lotte Hansen and Niels Jessen, Aarhus University

10.30

7:1

Combination of genetic and epigenetic sequencing approaches to unravel the altered gene regulatory structure in cancer, Jörg Tost, the National Genotyping Center, Evry, France

11.00

7:2

The use of genetic variation to predict age-related diseases as cardiovascular disease and dementia, Ruth Frikke-Schmidt, Copenhagen University Hospital, Denmark

11.20

7:3

Pharmacogenetics of metformin, Mette Marie H. Christensen, University of Southern Denmark, Odense, Denmark

11.40

7:4

Free communication 1: Mutations in the human SLC34A2 gene – characterization and effect on phosphate transport in Pulmonary Alveolar Microlithiasis, Åsa Jönsson, Dept. Biomedicine, Aarhus University

11.50

7:5

Free communication 2: Treatment with metformin improves endothelial function in aortic tissue and microvascular endothelial cells subjected to diabetic hyperglycaemic conditions, Chris Triggle, Pharmacology, Weill Cornell Medical College in Qatar

 

12.00-13.30

Stakladen

 

Lunch

12.15

Preben Hornung stuen

 

General Assembly

 

13.30-15.00

Preben Hornung

stuen

 

Session 8 - The devil is in the detail 

(co-sponsored with British Pharmacological Society)

Chairmen: Nanna MacAulay, Copenhagen University, Bryndis Birnir, Upssala University

13.30

8:1

Kv7.4 and Kv7.5 guardians of smooth muscle excitability, Iain Greenwood, Institute of Cardiovascular & Cell Sciences, St. George’s, University of London, UK

14.00

8:2

Functional roles of Kv7 channels in the hippocampal-entorhinal memory system, Johan Frederik Storm, Dept. Physiology, University of Oslo, Norway

14.20

8:3

Role of Kv7.1 in insulin secretion, Nicole Schmitt, Dept. Biomedicine, Copenhagen University, Denmark

14.40

8:4

Free communication 1: Altered stiffness in coronary arteries and effect of pirfernidone on endothelium-dependent vasodilatation in type 2 diabetic (db/db) mice, Lilliana Beck, Dept. Biomedicine, Aarhus University, Denmark

14.50

8:5

Free communication 2: Inhibition of Kv7 channels protects against myocardial ischemia and reperfusion injury, Elise Røge Hedegaard, Dept. Biomedicine, Aarhus University, Denmark

 

13.30-15.00

Richard Mortensen stuen

 

Session 9 - Cold news

Chairmen: Tobias Wang and Angela Fago, Aarhus University

13.30

9:1

Central nervous system control of hibernation reveals opportunities for human hibernation, Kelly Drew, Institute of Arctic Biology, University of Alaska Fairbanks, USA

14.00

9:2

Are you dead, just because you are cold? Benedict Kjærgaard, Biomedical Research Laboratory, Region Nordjylland, Denmark

14.20

9:3

Power napping extreme - hibernation in primates, Kathrin Dausmann, Animal Ecology and Conservation, Biocentre Grindel, University of Hamburg, Germany

14.40

9:4

Free communication 1: Regulation of hemoglobin oxygen affinity in hibernating animals, Angela Fago, Dept. Bioscience, Aarhus University

14.50

9:5

Free communication 2: The physiology of chill susceptibility in insects, Johannes Overgaard, Dept. Bioscience, Aarhus University

 

15.00-15.30

Stakladen

 

Coffee

15.30-17.00

Preben Hornung

stuen

 

Session 10 - The broken heart 

Chairmen: Vladimir Matchkov, Aarhus University, Bill Louch, Olso University

15.30

10:1

Physiology of hibernation as an angle to understand heart failure, Ole Frøbert, Department Cardiology, Örebro University, Sweden

16.00

10:2

The Pathophysiology of the broken heart, Elmir Omerovic, Institute of Medicine, University of Göthenborg, Sweden

16.20

10:3

Cardiac serotonin receptors and natriuretic peptide receptors as potential targets for heart failure therapy, Finn Olav Levy, Dept. Pharmacology, University of Oslo, Norway

16.40

10:4

Free communication 1: Circadian Rhythms in Cardiac Electrophysiology, Lisa A. Gottlieb, Dept. Biomedical Sciences, University of Copenhagen, Denmark

16.50

10:5

Free communication 2: BIN1 regulates t-tubule growth during development and disease, David Lipsett, Inst. For Experimental Medical Research, Oslo University Hospital, Norway

 

15.30-17.00

Richard Mortensen stuen

 

Session 11 - The marathon man

Chairmen: Ole Bækgaard Nielsen, Aarhus University, Ylva Hellsten, Copenhagen University

15.30

11:1

Oxygen uptake dynamics during exercise, Andrew M. Jones, Sport and Health Sciences, College of Life and Environmental Sciences, University of Exeter, UK

16.00

11:2

Maximal heart rate and cardiovascular capacity in humans, Dr. Stefan P. Mortensen, Dept. Molecular Medicine, University of Southern Denmark

16.20

11:3

Blood flow restricted and traditional resistance training produce equal muscle hypertrophy when performed to fatigue, Frank de Paoli, Dept. Biomedicine, Aarhus University

16.40

11:4

Free communication 1: Skeletal muscle dysfunction in the db/db mouse model of type 2 diabetes, Jeppe Seamus Bayley, Dept. Biomedicine, Aarhus University

16.50

11:5

Free communication 2: Regional differences in signaling pathways activity and gene expression levels in rat gastrocnemius muscle after a series of intense contractions, Anna Borzykh, SRC RF, Inst. For Biomedical Problems, Moscow, Russia

 

17.00-17.40

The Main Hall (Aulaen)

Plenary and Public lectures

introduced by Jens Leipziger, Aarhus University

 

Purinergic signaling in the lung: from bench to bedside and back again, Marco Idzko, University Hospital, Freiburg, Germany

17.45

 

Bus to Gala dinner at Moesgaard Museum

Sunday, 20th September

9.00-9.30

The Main Hall (Aulaen)

Plenary and Public lectures

introduced by Tomi Taira, Helsinki University

 

The nightlife of the brain, Maiken Nedergaard, Center of Basic and Translational Neuroscience, Copenhagen University, Denmark

9.40-11.10

Preben Hornung

stuen

 

Session 12 - High blood pressure becomes less essential

Chairmen: Pernille B. Lærkegaard Hansen, University of Southern Denmark, Peter Rossing, Steno Diabetes Center, Copenhagen

9.40

12:1

Defects of plasma membrane proteins: The first step to hyperaldosteronism? Richard Warth, Medical Cell Biology, Institute of Physiology Regensburg, Germany

10.10

12:2

Primary aldosteronism - from genetic abnormalities to pathophysiological models, Maria-Christina Zennaro, INSERM, U970, Paris Cardiovascular Research Center – PARCC Paris, France

10.30

12:3

Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension, Hanne Poulsen, Dept. Biomedicine, Aarhus University, Denmark

10.50

12:4

Free communication 1: Angiotensin II AT1-receptor blockade using Losartan does not impair renal oxygenation following hemorrhage, Jacqueline Melville, Dept. Medical Cell Biology, Uppsala University, Sweden

11.00

12:5

Free communication 2: Deficiency of the T-type calcium channel Cav3.1 attenuates plasma aldosterone and cardiac hypertrophy despite similar AngII-induced hypertension, Anne Daugaard Thuesen,

Dept. Molecular Medicine, University of Southern Denmark, Odense, Denmark

 

9.40-11.10

Richard Mortensen stuen

 

Session 13 - Urgent matters

Chairmen: Chris Fry, University of Bristol, Karl Erik Andersson, Aarhus University

9.40

13:1

The role of the mucosa in normal and abnormal bladder function, Chris Fry, School of Physiology and Pharmacology, University of Bristol, UK

10.10

13:2

MicroRNAs in bladder outlet obstruction: relationship to matrix remodelling and growth, Karl Swärd, Dept. Physiology, Lund University, Sweden

10.30

13:3

Inhibitory effects of urothelium-related factors, including PGD2, in guinea-pig urinary bladder, Lars E Gustafsson, Dept. Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden

10.50

13:4

Free communication 1: Role of SK3 channels in rectile function in mice, Simon Comerma-Steffensen, Dept. Biomedicine, Aarhus University

11.00

13:5

Free communication 2: Interstitial Cajal-like cells in the female reproductive tract, Sergey Machado-Abakumov, Dept. Biomedicine, Aarhus University

 

11.10-11.30

Stakladen

 

Coffee and exhibitors

11.30-13.00

Preben Hornung

stuen

 

Session 14 - Top flow

Chairmen: Leif Østergaard and Christian Aalkjær, Aarhus University,

11.30

14:1

Capillary flow patterns and brain oxygenation, Leif Østergaard, Dept. Neuroradiology, Aarhus University, Denmark

11.50

14:2

Capillary pericytes in health and disease, Catherine Hall, Sussex Neuroscience, University of Sussex and University College London, UK

12.15

 

14:3

Measuring microscopic flow patterns and brain oxygenation, Sava Sakadzic, Harvard Medical School, Boston, USA

12.40

14:4

Free communication 1: The α-2 isoform of Na,K-ATPase Modulates Vascular Tone via Activation of Src-kinase (Src) Signaling Pathway: a Lesson from Mouse model for Familial Hemiplegic Migraine Type 2 (FHM2), Vladimir Matchkov, Dept. Biomedicine, Aarhus University

12.50

 

14:5

Free communication 2: Changes in vasoreactivity following middle cerebral artery occlusion, André Erdling, Experimental Vascular Research, Lund University, Sweden

 

11.30-13.00

Richard Mortensen stuen

 

Session 15 - Moving Lipids

Chairmen Karin Lykke-Hartmann, University of Aarhus, Jens Peter Andersen, University of Aarhus

11.30

15:1

ATP-dependent Lipid Pumps:  Linking Lipid Transport to Cell Function and Disease, Robert S. Molday, Dept. Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada

12.00

15:2

Lipid pumps and ion pumps: how different are they? Jens P. Andersen, Dept. Biomedicine, Aarhus University, Denmark

12.25

15:3

The role of lipid flippases in bile formation, Coen Paulusma, Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, Netherlands

12.50

15:4

Free communication 1: Biochemical characterization of P4-ATPase mutations associated with intrahepatic cholestatic disease, Rasmus H. Gantzel, Dept. Biomedicine, Aarhus University, Denmark

13.00-13.30

Stakladen

 

Lunch

13.30-15.00

Preben Hornung

stuen

 

Session 16 - Mind your molecules

Chairmen: Marina Romero-Ramos, Aarhus University, Ole Bjerrum Copenhagen University

13.30

16:1

Using molecular genetics to short the circuitry of memory Cliff Kentros, Kavli Institute of Systems Neuroscience, Trondheim, Norway

14.00

16:2

The Arc of synaptic memory, Clive Bramham, Dept. Biomedicine, University of Bergen

14.25

16:3

I can make you move! – the remote control of nerve cell transplants, Tomas Björklund, Dept. Experimental Medical Science, Lund University.

14.50

16:4

Free communication 1: Mapping the dualistic profile of an allosteric AMPA receptor modulator-studies on recombinant receptors, mouse hippocampal synapses and crystal structures, Mai Marie Holm, Dept. Biomedicine, Aarhus University

13.30-15.00

Richard Mortensen stuen

 

Session 17 - Into thin blood

Chairmen: Anne Mette Hvas, Aarhus University, Rickard Malmström, Karolinska Institutet, Stockholm

13.30

17:1

New mechanisms and targets for antiplatelet and anticoagulation therapy, Robert Flaumenhaft, Harvard Medical School, Boston, USA

14.00

17:2

Novel oral anticoagulants and the clinical pharmacological/therapeutic aspect of therapeutic drug monitoring, Rickard Malmström, Dept. Medicine Solna, Karolinska Institutet, Stockholm

14.20

17:3

Aspirin in coronary artery disease: potential causes of reduced antiplatelet effect, Anne-Mette Hvas, Aarhus University

14.40

17:4

Free communication 1: Dual activation of the bile acid nuclear receptor FXR and G-protein-coupled receptor TGR5 attenuates lithium-induced nephrogenic diabetes insipidus, Weidong Wang, Sun Yat-sen University, Guangzhou, China

14.50

17:5

Free communication 2: Right ventriculo-arterial interaction in health and disease as assessed by wave intensity analysis, Junjing Su, Dept. Biomedicine, Aarhus University

 

15.00

 

End of Meeting