SAVE_THE_DATE!
It is with great pleasure that we announce that the 3rd International Moesgaard Conference on Personalised Medicine in Aarhus will be held on October 5th-6th 2027.
More information will follow.
Professor
Research unit of Clincial Genetics (Odense),
University of Southern Denmark
Associate Professor
Department of Clinical Medicine
Aalborg University
Clinical Professor
Department of Clinical Medicine
Copenhagen University
Professor
Novo Nordisk Foundation Center for Protein Research
Copenhagen University
Professor
Department of Public Health
University of Southern Denmark
8:30-9:00 Coffee and registration
9:00-9:15 Opening of meeting Anne-Mette Hvas, Dean at the Faculty of Health, Aarhus University, Denmark
Welcome remarks Anders Børglum, Managing Professor of the Personalised Medicine Network, Aarhus University, Denmark
SESSION I: “HUMAN DIVERSITY” (Chair: Anders Børglum)
9:15-10:05 Opening Keynote: Study of human diversity Kári Stefánsson, deCode Genetics, Iceland
10:05-10:35 Genetics of ADHD – risk loci and genetic overlap with other phenotypes Ditte Demontis, Aarhus University, Denmark
10:35-10:50 Systematic investigation of allelic regulatory activity of psychiatric disorder risk variants Hyejung Won, University of North Carolina at Chapel Hill, NC, USA
10:50-11:10 Coffee with light refreshment, poster viewing and networking
SESSION II: “TOWARDS PERSONALISED PSYCHIATRY” (Chairs: Doug Speed & Ole Köhler-Forsberg)
11:10-12:00 Keynote: The potential and the barriers for genetic personalised medicine in psychiatry Cathryn Lewis, Kings College London, United Kingdom
12:00-12:30 Polygenic aspects of childhood neurodevelopmental disorders Jakob Grove, Aarhus University, Denmark
12:30-12:40 Flash talk: Polygenic liabilities and treatment trajectories in early-onset depression (presenter: Jessica Mundy)
12:40-13:35 Lunch and networking
13:35-15:05 Poster session and coffee & cake
SESSION III: “DISEASE PROGRESSION AND PHENOTYPIC VARIATION” (Chairs: Claus Gravholt & Camilla Blunk Brandt)
15:05-15:35 Deep learning approaches for analysis of population-wide disease progression data Søren Brunak, University of Copenhagen, Denmark
15:35-16.05 Expanding the phenotypic spectrum of calmodulinopathies Mette Nyegaard, Aalborg University, Denmark
16:05-16:35 Introducing a decision support tool - The Ischemic Heart Disease Algorithm - in clinical practice - a randomised clinical trial Henning Bundgaard, Rigshospitalet, Copenhagen, Denmark
16:35-16:55 Flash talks: Exploring the impact of BMI on cancer development (presenter: Johanne Ahrenfeldt) The information system, a unique work tool to optimize drug safety during pregnancy (presenter: Line Kolding og Jakob N. Henriksen)
17:30-20:00 Conference dinner/reception
8:30-9:00 Coffee
SESSION IV: “ADVANCED STATISTICAL METHODS” (Chairs: Liselotte Vogdrup Petersen & Bjarni J. Vilhjálmson)
9:00-9:30 Mendelian Randomisation with Directed Acyclic Graphs learning: Opportunities and pitfalls in personalised medicine Leonardo Bottolo, University of Cambridge, United Kingdom
9:30-10:00 Machine learning with clinical purpose Adam Hulman, Aarhus University, Denmark
10:00-10:20 Flash talks: LDAK-PBAT: A Novel Pathway-Based Analysis Tool for Decoding the Genetics of Complex Diseases (presenter: Takiy Berrandou) Unraveling the regulation mechanism of the human flippase ATP8B1 (presenter: Poul Nissen)
10:20-10:50 Coffee with light refreshment, poster viewing and networking
SESSION V: “EPIDEMIOLOGICAL STUDIES” (Chairs: Uffe Birk Jensen & Hannah Chatwin)
10:50-11:40 Keynote: Using genetic epidemiology to inform personalised medicine Per Magnus, Norwegian Institute of Public Health, Norway
11:40-12:10 Early life exposures and pubertal development: results from the DNBC Puberty cohort Cecilia Ramlau-Hansen, Aarhus University, Denmark
12:10-13:10 Lunch and networking SESSION VI: “ADVANCED TECHNOLOGIES IN CANCER RESEARCH” (Chairs: Martin Bøgsted & Lars Dyrskjøt Andersen)
13:10-14:00 Keynote: Data-driven and functional precision medicine for acute myeloid leukemia and beyond Olli Kallioniemi, SciLifeLab and Karolinska Institute, Sweden
14:00-14:30 The power of circulating tumor cells in Immuno-Oncology Catherine Panabieres, University Medical Centre of Montpellier, France
14:30-15:00 T cell receptor landscape associate with metastasis in bladder cancer Nicolai Birkbak, Aarhus University, Denmark 15:00-15:30 Networking and coffee & cake SESSION VII: “APPLIED PERSONALISED MEDICINE” (Chairs: Deirdre Cronin Fenton & Mikkel Heide Schierup)
15:30-15:50 Flash talks: Social characteristics and adherence to adjuvant endocrine therapy in breast cancer patients (presenter: Julie Schmidt) Genetic variants of the serotonin transporter with functional and pharmacological impact (presenter: Steffen Sinning)
15:50-16:20 Treatment decisions for metastatic cancer patient – implementation of personalised medicine Britt Elmedal Laursen, Aarhus University, Denmark
16:20-16:45 Closing remarks, poster & flash talk awards
8:30-9:00 Coffee and registration
9:00-9:15 Opening of meeting Per B. Höllsberg, Vice-dean for Research at the Faculty of Health, Aarhus University, Denmark
Welcome remarks Anders Børglum, Managing Professor of the Personalised Medicine Network, Aarhus University, Denmark
SESSION I: Neuroscience and precision medicine (PM) perspectives (Chairs: Anders Børglum, Jakob Christensen & Nanna Møller Nielsen)
9:15-10:05 Opening Keynote: Instructions Included: Assembling Human Neural Ciruits to Study Disease and Develop Therapeutics
Sergiu Pasca, Stanford University, USA
10:05-10:35 Invited speaker: Neuron-specific immune signaling in memory
Jelena Radulovic, Aarhus University, Denmark
10:35-11:10 Coffee with light refreshment, poster viewing and networking
SESSION II: Utility of genetics in PM of common complex disorders (Chairs: Ditte Demontis, Doug Speed & Anne Lundager Madsen
11:10-12:00 Keynote: Using genetics and genomics to probe complexity vs heterogeneity in common disease
Naomi Wray, University of Oxford, UK
12:00-12:30 Invited speaker: Copenhagen Hospital Biobank & the Danish Blood Donor Study: Unique data resource for development of precision medicine
Sisse Ostrowski, University of Copenhagen & Rigshospitalet, Denmark
Flash talks:
12:30-12:40 Leveraging single-cell genomic annotations to improve polygenic prediction of psychiatric disorders -Jian Zeng, The University of Queensland
12:40 – 12:50 Biobank-scale modelling of circadian misalignment -Clara Albiñana, Big Data Institute, University of Oxford, NCRR, Aarhus University
12:50-13:45 Lunch and networking
13:45-15:00 Poster session and coffee & cake
SESSION III: Obesity, diabetes and precision medicine (Chairs: Niels Jessen, Tore Stage & Julie Bondgaard Løhde)
15:00-15:30 Keynote: Implementing precision diabetes care in the clinic
Ewan Pearson, University of Dundee, Scotland
15:30-16.00 Invited speaker: Between metabolic heterogeneity and psycho-social barriers: The long and winding road to precision prevention of type 2
diabetes Daniel Witte, Aarhus University, Denmark
16:00-16:30 Invited speaker: Personalised medicine in the diabetes clinic – a Danish perspective
Julie Støy, Aarhus University, Denmark
Flash talks:
16:30-16:40 Leveraging type 2 diabetes subtypes in GWAS reveals genetic heterogeneity and improves discovery - Jasper Hof, Center for Quantitive Genetics & Genomics, Aarhus University
16:40-16:50 Shared Genetic Architecture Between Endometriosis and Psychiatric Conditions May Explain Comorbidity - Marika Rostvall, Karolinska Institut
16:50-17:00 Patient in a dish: mimicking patient phenotypes in 3D adipocyte spheroids - Bianca E. Suur, Department of Biomedicine, Aarhus University
17:30-19:30 Conference dinner/reception
8:30-9:00 Coffee
SESSION IV: Cancer – data science & bioinformatics (Chairs: Deirdre Cronin Fenton, Uffe Brik Jensen & Trine Strandgaard)
9:00-9:30 Keynote: Rationalising the genomic and transcriptional heterogeneity in therapy resistant breast cancer
Rachael Natrajan, Institute of Cancer Research, UK
9:30-10:00 Invited speaker: Genomics and transcriptomics for personalized medicine in breast cancer
Mads Thomassen, University of Southern Denmark, Denmark
10:00-10:15 Invited speaker: Multiplexed imaging-powered deep visual proteomics
Xiang Zheng, Aarhus University, Denmark
Flash talks:
10:15-10:25 Cytosolic DNA Sensing is a Predictor of Clinical Outcomes in Bladder Cancer - Stine Høvring Godsk, Dept. of Molecular Medicine (MOMA), Aarhus University
10:25-10:35 Patient-derived cervical organoid-assembloid platforms for predictive and personalised medicine - Pon Ganish Prakash, Department of Biological and Chemical Engineering, Aarhus University
10:35-11:05 Coffee with light refreshment, poster viewing and networking
SESSION V: Multimodal data boosting PM (Chairs: Søren Brunak, Liselotte Vogdrup Petersen & TBA)
11:05-11:55 Keynote: Implementation of AI tools in healthcare for P4 medicine
Richard Dobson, King’s College London, UK
11:55-12:25 Invited speaker: Machine learning in psychiatry
Line H. Clemmensen,
University of Copenhagen, Denmark
Flash talks:
12:25-12:35 What dizygotic twinning can teach us about female fertility - Nikke Hubers, National Center for Register-based Research & SMARTbiomed, Aarhus University
12:35-12:45 Immune-to-brain mechanisms and neurocircuits of affective homeostasis - Anne Mathia Klawonn, Dandrite/Department of Biomedicine, Aarhus
University
12:45-13:30 Lunch and networking
13:30-14:45 Poster session and coffee & cake
SESSION VI: Novel therapeutic approaches (Chairs: Ole Köhler-Forsberg & Ronja Tügel Carstensen)
14:45-15:25 International speaker: Transforming the evidence landscape in mental health with platform trials
Stefan Gold, Charité Universitätsmedizin, Germany
15:25-15:50 Invited speaker: Biomarkers and drug transport in chemotherapy-induced peripheral neurotoxicity Tore Stage, University of Southern Denmark, Denmark
15:50-16:15 Invited speaker: Innovative Gene Therapy Approaches for Retinal Diseases Anne Louise Askou, Aarhus University & Aarhus University Hospital, Denmark
16:15-16:35 Invited speaker: Genomics-Driven Discovery of Novel Therapeutic Targets in Neurodevelopmental Disorders Vijay Tiwari, University of Southern Denmark, Denmark
16:35-16:45 Closing remarks, poster & flash talk awards
